Syphilis Symptoms: Signs, Stages, and Treatment Options


Syphilis is a sexually transmitted disease (STD) that has affected millions of people worldwide. It is caused by the Treponema pallidum bacterium and can be spread through sexual contact or from mother to child during pregnancy. It is a serious infection that can affect various parts of the body, including the brain, heart, nerves, and eyes if left untreated.

It is important to know the symptoms of syphilis to seek prompt medical attention. In this article, we will discuss the 10 common symptoms of syphilis, the stages, and how to identify symptoms at each stage. We will also focus on syphilis symptoms in women, understanding co-infection symptoms, and unusual signs and symptoms of syphilis.

10 Common Symptoms of Syphilis You Should Know About

Here are 10 common symptoms of syphilis:

  1. Chancre sores: Small, painless sores that appear on or around the genitals, anus, or mouth.
  2. Rash: A rash that can appear on the palms of the hands or the soles of the feet.
  3. Fever: A low-grade fever that may accompany other symptoms.
  4. Sore throat: A sore throat that can last for weeks with or without other symptoms.
  5. Hair loss: Patchy hair loss or thinning hair.
  6. Headaches: Persistent headaches that may be accompanied by neck stiffness.
  7. Fatigue: Tiredness and lack of energy even after rest.
  8. Weight loss: Unintentional weight loss.
  9. Muscle aches and joint pain: Pain in the muscles and joints.
  10. Swollen lymph nodes: Enlarged lymph nodes in the neck, groin or armpits.

If you experience any of these symptoms, it is important to see a healthcare provider as soon as possible.

The Stages of Syphilis: Identifying Symptoms from Primary to Tertiary

Syphilis progresses through three stages:

Primary Stage

The primary stage of syphilis is marked by the appearance of a chancre sore. This sore may be mistaken for a harmless bump or sore and goes unnoticed, but it is highly infectious. The sore typically appears several days to a few weeks after infection and lasts for 3-6 weeks before healing on its own.

Secondary Stage

The secondary stage of syphilis typically occurs within a few weeks of the appearance of the chancre sore. Symptoms of the secondary stage may include:

  • A non-itchy rash on the palms, soles of the feet, or other parts of the body.
  • Fever and flu-like symptoms.
  • Sore throat and swollen lymph nodes.
  • Headaches, muscle aches, and fatigue.
  • Hair loss or patches of baldness.

Tertiary Stage

The tertiary stage of syphilis can occur several years after the initial infection, and it is the most severe stage. Symptoms of tertiary syphilis can include:

  • Neurological problems which can lead to dementia, blindness, or paralysis.
  • Cardiovascular problems, which can cause aneurysms and heart failure.
  • Organ damage, including damage to the liver, bones, and joints.

If syphilis is left untreated, it can lead to serious health problems.

Syphilis Symptoms in Women: Recognizing the Signs and Seeking Treatment

Syphilis symptoms can differ between men and women. In women, symptoms of syphilis can include:

  • An unusual discharge from the vagina.
  • Pain during sex, bleeding after sex, or bleeding between periods.
  • Painful urination
  • Rash or small sores around the genitals or anus.

It is important for women to understand the symptoms of syphilis and seek treatment as soon as possible. A pregnant woman with untreated syphilis can pass the infection on to her baby, which can lead to stillbirth or other health problems.

The Link Between HIV and Syphilis: Understanding Co-Infection Symptoms

People with HIV are more likely to contract syphilis, and people with syphilis are at an increased risk of contracting HIV. Given this link, it is important to understand the symptoms of co-infection.

Symptoms of co-infection may include:

  • Fever and flu-like symptoms.
  • Rashes and sores throughout the body.
  • An increased risk of eye disease and loss of vision.
  • An increased risk of neurological disorders.

Anyone who is sexually active should take precautions to prevent both HIV and syphilis.

Beyond Sores: Unusual Signs and Symptoms of Syphilis You Need to Be Aware Of

In addition to the common symptoms outlined above, syphilis can sometimes present with unusual symptoms. These may include:

  • No obvious symptoms, which can make syphilis difficult to detect.
  • Joint pain and swelling.
  • Mouth ulcers or sores that do not heal.
  • Kidney problems.
  • Unusual weight loss or gain.

It is important to be aware of these symptoms and seek medical attention if you suspect you may have syphilis.


Knowing the symptoms of syphilis is critical to preventing serious health problems. Recognizing the symptoms and seeking treatment can prevent the spread of the infection and enable prompt treatment before the infection progresses into later stages.

Regardless of the type of syphilis symptoms you experience, it is essential to seek immediate attention from a healthcare provider. Prompt detection of syphilis ensures an appropriate course of treatment to prevent fatal complications.

Protecting yourself from syphilis is part of taking care of your sexual health. By using protection during sexual intercourse, getting regular checkups if you have multiple sexual partners or are exposed to STDs, and treating any STDs as soon as they emerge, you can reduce your chances of contracting syphilis or other STDs.

Webben Editor

Hello! I'm Webben, your guide to intriguing insights about our diverse world. I strive to share knowledge, ignite curiosity, and promote understanding across various fields. Join me on this enlightening journey as we explore and grow together.

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